Evidence
Research and sources
The primary sources SemenBoost uses for semen analysis, male infertility and UK sperm storage.
- Published
- Modified
- Clinician review
- Complete
Short answer
SemenBoost prefers the organisation that owns the method or the recommendation. For semen numbers that is the WHO laboratory manual. For UK care it is NICE NG257 and the NHS. For US specialist practice it is AUA/ASRM. For UK storage and licensed clinics it is the HFEA. Systematic reviews outrank supplement brands.
Key takeaways
- Reference limits on this site match NICE NG257’s quotation of the WHO 6th edition.
- The antioxidant Cochrane review is the context for supplement outcome claims.
- A source can support a semen finding and still not support a pregnancy claim.
- This page is a map, not a library of every paper.
Primary sources
- WHO laboratory manual, 6th edition
- NICE NG257, published 31 March 2026
- NHS: low sperm count
- AUA/ASRM male infertility guideline
- AUA testosterone deficiency guideline
- HFEA: sperm freezing
- Cochrane: antioxidants for male subfertility
How claims are limited
If NICE says the impact of smoking on male fertility is uncertain, the smoking page says that. If a zinc trial finds no live-birth benefit, the zinc page does not cite an earlier positive abstract instead. If a varicocele trial reports pregnancy but not live birth, the evidence rating says so.
Updates
Guideline changes are editorial events. A scheduled job may later flag that a source page has changed. It may not publish a new reference limit. See the medical review policy.
Related
Sources
- WHO laboratory manual for the examination and processing of human semen, 6th edition — World Health Organization, 2021
- Fertility problems: assessment and treatment (NG257) — NICE, 2026
- Low sperm count — NHS
- Diagnosis and Treatment of Infertility in Men: AUA/ASRM Guideline (amended 2024) — American Urological Association, 2024
- Evaluation and Management of Testosterone Deficiency: AUA Guideline — American Urological Association
- Sperm freezing — Human Fertilisation and Embryology Authority
- Antioxidants for male subfertility — Cochrane, 2022
How this page was prepared
Editorial page for SemenBoost. It explains how the site works. It is not a clinical recommendation.